gc; GPCRSECRETIN
gx; PR00249
gn; COMPOUND(7)
ga; 27-JUL-1992; UPDATE 19-JUN-1999
gt; Secretin-like GPCR superfamily signature
gp; PRINTS; PR00237 GPCRRHODOPSN; PR00247 GPCRCAMP; PR00248 GPCRMGR
gp; PRINTS; PR00250 GPCRSTE2; PR00899 GPCRSTE3; PR00251 BACTRLOPSIN
gp; PRINTS; PR01694 BAIPRECURSOR; PR01350 CTRFAMILY; PR01278 CD97PROTEIN
gp; PRINTS; PR01279 CRFRECEPTOR; PR01127 DIUHORMONER; PR01128 EMR1HORMONER
gp; PRINTS; PR01352 GHRHRECEPTOR; PR01129 GIPRECEPTOR; PR01353 GLUCAGNFAMLY
gp; PRINTS; PR01695 IGHEPTARCPTR; PR01444 LATROPHILIN; PR00393 PTRHORMONER
gp; PRINTS; PR00490 SECRETINR; PR00491 VASOACTVEIPR; PR01422 GPR56ORPHANR
gp; INTERPRO; IPR000832
gp; PROSITE; PS00649 G_PROTEIN_RECEP_F2_1; PS00650 G_PROTEIN_RECEP_F2_2
gp; PFAM; PF00002 7tm_2
bb;
gr; 1. ATTWOOD, T.K. AND FINDLAY, J.B.C.
gr; Fingerprinting G protein-coupled receptors.
gr; PROTEIN ENG. 7(2) 195-203 (1994). 
gr;
gr; 2. ISHIHARA T., NAKAMURA S., KAZIRO, Y., TAKAHASHI, T., TAKAHASHI, K.
gr; AND NAGATA, S.
gr; Molecular cloning and expression of a cDNA encoding the secretin receptor
gr; EMBO J. 10 1635-1641 (1991).
gr; 
gr; 3. LIN, H.Y., HARRIS, T.L., FLANNERY, M.S., ARUFFO, A., KAJI, E.H., 
gr; GORN, A., KOLAKOWSKI, L.F., LODISH, H.F. AND GOLDRING, S.R.
gr; Expression cloning of adenylate cyclase-coupled calcitonin receptor
gr; SCIENCE 254 1022-1024 (1991).
gr;
gr; 4. JUEPPNER, H., ABOU-SAMRA, A.-B., FREEMAN, M., KONG, X.F., 
gr; SCHIPANI, E., RICHARDS, J., KOLALOWSKI, L.F., HOCK, J., POTTS, J.T.,
gr; KRONENBERG, H.M. AND SEGRE, G.E.
gr; A G protein linked receptor for parathyroid hormone and parathyroid
gr; hormone-related peptide.
gr; SCIENCE 254 1024-1026 (1991).
gr;
gr; 5. ISHIHARA, T., SHIGEMOTO, R., MORI, K., TAKAHASHI, K. AND NAGATA, S.
gr; Functional expression and tissue distribution of a novel receptor for
gr; vasoactive intestinal polypeptide.
gr; NEURON 8(4) 811-819 (1992).
bb;
bb;
gd; G protein-coupled receptors (GPCRs) constitute a vast protein family that 
gd; encompasses a wide range of functions (including various autocrine, para-
gd; crine and endocrine processes). They show considerable diversity at the 
gd; sequence level, on the basis of which they can be separated into distinct 
gd; groups. We use the term clan to describe the GPCRs, as they embrace a group
gd; of families for which there are indications of evolutionary relationship, 
gd; but between which there is no statistically significant similarity in 
gd; sequence [1]. The currently known clan members include the rhodopsin-like 
gd; GPCRs, the secretin-like GPCRs, the cAMP receptors, the fungal mating
gd; pheromone receptors, and the metabotropic glutamate receptor family.
gd; 
gd; The secretin-like GPCRs include secretin [2], calcitonin [3], parathyroid
gd; hormone/parathyroid hormone-related peptides [4] and vasoactive intestinal
gd; peptide [5], all of which activate adenylyl cyclase and the phosphatidyl-
gd; inositol-calcium pathway. The amino acid sequences of the receptors contain
gd; high proportions of hydrophobic residues grouped into 7 domains, in a
gd; manner reminiscent of the rhodopsins and other receptors believed to inter-
gd; act with G proteins. However, while a similar 3D framework has been
gd; proposed to account for this, there is no significant sequence similarity
gd; between these families: the secretin-like receptors thus bear their own
gd; unique '7TM' signature.
gd;
gd; GPCRSECRETIN is a 7-element fingerprint that provides a signature for the 
gd; secretin-like GPCR superfamily. The fingerprint was derived from an initial
gd; alignment of 4 sequences: the motifs encode the 7 hydrophobic, membrane-
gd; spanning regions (cf. PROSITE pattern PS00650 G_PROTEIN_RECEP_F2_2). A 
gd; single iteration on OWL17.0 was required to reach convergence, no further
gd; sequences being identified beyond the starting set. 
gd;
gd; An update on SPTR37_9f identified a true set of 59 sequences, and 15
gd; partial matches.
bb;
bb;
si; SUMMARY INFORMATION
si; -------------------
sd;   59 codes involving  7 elements
sd;    0 codes involving  6 elements
sd;    1 codes involving  5 elements
sd;    2 codes involving  4 elements
sd;    1 codes involving  3 elements
sd;   11 codes involving  2 elements
bb;
bb;
ci; COMPOSITE FINGERPRINT INDEX
ci; ---------------------------
cr;
cd;  7|  59   59   59   59   59   59   59  
cd;  6|   0    0    0    0    0    0    0  
cd;  5|   1    0    1    1    1    0    1  
cd;  4|   0    1    2    2    2    1    0  
cd;  3|   1    0    1    0    1    0    0  
cd;  2|   8    0   10    3    0    0    1  
cd; --+------------------------------------
cd;   |   1    2    3    4    5    6    7  
bb;
bb;
tp; VIPR_RAT       SCRC_RAT       SCRC_HUMAN     PACR_RAT       
tp; PACR_MOUSE     PACR_HUMAN     O73769         PACR_BOVIN     
tp; SCRC_RABIT     VIPR_HUMAN     VIPR_PIG       VIPS_HUMAN     
tp; PTRR_HUMAN     PTRR_DIDMA     PTRR_PIG       VIPR_CARAU     
tp; VIPS_MOUSE     VIPS_RAT       PTRR_MOUSE     PTRR_RAT       
tp; O73768         GIPR_RAT       GIPR_HUMAN     GIPR_MESAU     
tp; GLR_RAT        GLPR_RAT       GLR_MOUSE      GLPR_MOUSE     
tp; GLR_HUMAN      GLPR_HUMAN     CRFR_MOUSE     CRFR_SHEEP     
tp; CRFR_HUMAN     CRFR_RAT       CRFR_XENLA     CRF2_RAT       
tp; PTR2_HUMAN     GRFR_PIG       Q99431         O43461         
tp; CRF2_HUMAN     GRFR_HUMAN     PTH2_RAT       GRFR_RAT       
tp; CRF2_MOUSE     GRFR_MOUSE     CRFR_CHICK     CRF2_XENLA     
tp; CALR_CAVPO     CALR_HUMAN     CALR_RABIT     CALR_RAT       
tp; CALR_MOUSE     CALR_PIG       DIHR_MANSE     CGRR_HUMAN     
tp; CGRR_RAT       DIHR_ACHDO     Q93245         
bb;
sn; Codes involving 5 elements
st; YQ44_CAEEL     
bb;
sn; Codes involving 4 elements
st; Q98955         YOW3_CAEEL     
bb;
sn; Codes involving 3 elements
st; EMR1_HUMAN     
bb;
sn; Codes involving 2 elements
st; Q10922         EMR1_MOUSE     O88929         O88928         
st; O88927         O88926         O88925         O88924         
st; CD97_HUMAN     O00718                  
bb;
bb;
tt; VIPR_RAT         VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 PRECURSOR (VIP-R-1) (PITUITARY ADEN
tt; SCRC_RAT         SECRETIN RECEPTOR PRECURSOR (SCT-R) - RATTUS NORVEGICUS (RAT).
tt; SCRC_HUMAN       SECRETIN RECEPTOR PRECURSOR (SCT-R) - HOMO SAPIENS (HUMAN).
tt; PACR_RAT         PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE IA RECEPTOR PRECURSOR (P
tt; PACR_MOUSE       PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE I RECEPTOR PRECURSOR (PA
tt; PACR_HUMAN       PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE I RECEPTOR PRECURSOR (PA
tt; O73769           PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE 1 RECEPTOR PRECURSOR - C
tt; PACR_BOVIN       PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE I RECEPTOR PRECURSOR (PA
tt; SCRC_RABIT       SECRETIN RECEPTOR PRECURSOR (SCT-R) - ORYCTOLAGUS CUNICULUS (RABBIT).
tt; VIPR_HUMAN       VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 PRECURSOR (VIP-R-1) (PITUITARY ADEN
tt; VIPR_PIG         VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 PRECURSOR (VIP-R-1) (PITUITARY ADEN
tt; VIPS_HUMAN       VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 PRECURSOR (VIP-R-2) (PITUITARY ADEN
tt; PTRR_HUMAN       PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR PRECURSOR (PTH/
tt; PTRR_DIDMA       PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR PRECURSOR (PTH/
tt; PTRR_PIG         PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR PRECURSOR (PTH/
tt; VIPR_CARAU       VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR (VIP-R) (VIP RECEPTOR) - CARASSIUS AU
tt; VIPS_MOUSE       VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 PRECURSOR (VIP-R-2) (PITUITARY ADEN
tt; VIPS_RAT         VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 PRECURSOR (VIP-R-2) (PITUITARY ADEN
tt; PTRR_MOUSE       PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR PRECURSOR (PTH/
tt; PTRR_RAT         PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR PRECURSOR (PTH/
tt; O73768           GROWTH-HORMONE RELEASING HORMONE-LIKE PEPTIDE RECEPTOR - CARASSIUS AURATUS (GOLD
tt; GIPR_RAT         GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR PRECURSOR (GIP-R) (GLUCOSE- DEPENDENT IN
tt; GIPR_HUMAN       GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR PRECURSOR (GIP-R) (GLUCOSE- DEPENDENT IN
tt; GIPR_MESAU       GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR PRECURSOR (GIP-R) (GLUCOSE- DEPENDENT IN
tt; GLR_RAT          GLUCAGON RECEPTOR PRECURSOR (GL-R) - RATTUS NORVEGICUS (RAT).
tt; GLPR_RAT         GLUCAGON-LIKE PEPTIDE 1 RECEPTOR PRECURSOR (GLP-1 RECEPTOR) (GLP-1-R) - RATTUS N
tt; GLR_MOUSE        GLUCAGON RECEPTOR PRECURSOR (GL-R) - MUS MUSCULUS (MOUSE).
tt; GLPR_MOUSE       GLUCAGON-LIKE PEPTIDE 1 RECEPTOR PRECURSOR (GLP-1 RECEPTOR) (GLP-1-R) - MUS MUSC
tt; GLR_HUMAN        GLUCAGON RECEPTOR PRECURSOR (GL-R) - HOMO SAPIENS (HUMAN).
tt; GLPR_HUMAN       GLUCAGON-LIKE PEPTIDE 1 RECEPTOR PRECURSOR (GLP-1 RECEPTOR) (GLP-1-R) - HOMO SAP
tt; CRFR_MOUSE       CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 PRECURSOR (CRF-R) (CRF1) - MUS MUSCULU
tt; CRFR_SHEEP       CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 PRECURSOR (CRF-R) (CRF1) - OVIS ARIES 
tt; CRFR_HUMAN       CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 PRECURSOR (CRF-R) (CRF1) - HOMO SAPIEN
tt; CRFR_RAT         CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 PRECURSOR (CRF-R) (CRF1) - RATTUS NORV
tt; CRFR_XENLA       CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 PRECURSOR (CRF-R) (CRF1) - XENOPUS LAE
tt; CRF2_RAT         CORTICOTROPIN RELEASING FACTOR RECEPTOR 2 PRECURSOR (CRF-R) (CRF2) - RATTUS NORV
tt; PTR2_HUMAN       PARATHYROID HORMONE RECEPTOR PRECURSOR (PTH2 RECEPTOR) - HOMO SAPIENS (HUMAN).
tt; GRFR_PIG         GROWTH HORMONE-RELEASING HORMONE RECEPTOR PRECURSOR (GHRH RECEPTOR) (GRF RECEPTO
tt; Q99431           CORTICOTROPIN RELEASING HORMONE RECEPTOR TYPE 2 BETA ISOFORM (CRF2 RECEPTOR, BET
tt; O43461           CORTICOTROPIN RELEASING HORMONE RECEPTOR TYPE 2 GAMMA ISOFORM - HOMO SAPIENS (HU
tt; CRF2_HUMAN       CORTICOTROPIN RELEASING FACTOR RECEPTOR 2 PRECURSOR (CRF-R) (CRF2) - HOMO SAPIEN
tt; GRFR_HUMAN       GROWTH HORMONE-RELEASING HORMONE RECEPTOR PRECURSOR (GHRH RECEPTOR) (GRF RECEPTO
tt; PTH2_RAT         PARATHYROID HORMONE RECEPTOR PRECURSOR (PTH2 RECEPTOR) - RATTUS NORVEGICUS (RAT)
tt; GRFR_RAT         GROWTH HORMONE-RELEASING HORMONE RECEPTOR PRECURSOR (GHRH RECEPTOR) (GRF RECEPTO
tt; CRF2_MOUSE       CORTICOTROPIN RELEASING FACTOR RECEPTOR 2 PRECURSOR (CRF-R) (CRF2) (CRF-RB) (CRH
tt; GRFR_MOUSE       GROWTH HORMONE-RELEASING HORMONE RECEPTOR PRECURSOR (GHRH RECEPTOR) (GRF RECEPTO
tt; CRFR_CHICK       CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 PRECURSOR (CRF-R) (CRF1) - GALLUS GALL
tt; CRF2_XENLA       CORTICOTROPIN RELEASING FACTOR RECEPTOR 2 PRECURSOR (CRF-R) (CRF2) - XENOPUS LAE
tt; CALR_CAVPO       CALCITONIN RECEPTOR PRECURSOR (CT-R) - CAVIA PORCELLUS (GUINEA PIG).
tt; CALR_HUMAN       CALCITONIN RECEPTOR PRECURSOR (CT-R) - HOMO SAPIENS (HUMAN).
tt; CALR_RABIT       CALCITONIN RECEPTOR PRECURSOR (CT-R) - ORYCTOLAGUS CUNICULUS (RABBIT).
tt; CALR_RAT         CALCITONIN RECEPTOR PRECURSOR (CT-R) (C1A/C1B) - RATTUS NORVEGICUS (RAT).
tt; CALR_MOUSE       CALCITONIN RECEPTOR PRECURSOR (CT-R) - MUS MUSCULUS (MOUSE).
tt; CALR_PIG         CALCITONIN RECEPTOR PRECURSOR (CT-R) - SUS SCROFA (PIG).
tt; DIHR_MANSE       DIURETIC HORMONE RECEPTOR (DH-R) - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HOR
tt; CGRR_HUMAN       CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR PRECURSOR (CGRP TYPE 1 RECEPTOR)
tt; CGRR_RAT         CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR PRECURSOR (CGRP TYPE 1 RECEPTOR)
tt; DIHR_ACHDO       DIURETIC HORMONE RECEPTOR PRECURSOR (DH-R) - ACHETA DOMESTICUS (HOUSE CRICKET).
tt; Q93245           C18B12B.1.
tt;
tt; YQ44_CAEEL       PROBABLE G PROTEIN-COUPLED RECEPTOR C13B9.4 IN CHROMOSOME III - CAENORHABDITIS E
tt;
tt; Q98955           GLUCAGON RECEPTOR - MELEAGRIS GALLOPAVO (COMMON TURKEY).
tt; YOW3_CAEEL       PROBABLE G PROTEIN-COUPLED RECEPTOR ZK643.3 - CAENORHABDITIS ELEGANS.
tt;
tt; EMR1_HUMAN       CELL SURFACE GLYCOPROTEIN EMR1 PRECURSOR (EMR1 HORMONE RECEPTOR) - HOMO SAPIENS 
tt;
tt; Q10922           HYPOTHETICAL 174.3 KD PROTEIN B0286.2 IN CHROMOSOME II - CAENORHABDITIS ELEGANS.
tt; EMR1_MOUSE       CELL SURFACE GLYCOPROTEIN EMR1 PRECURSOR (EMR1 HORMONE RECEPTOR) (CELL SURFACE G
tt; O88929           CL3BC - RATTUS NORVEGICUS (RAT).
tt; O88928           CL3BB - RATTUS NORVEGICUS (RAT).
tt; O88927           CL3BA - RATTUS NORVEGICUS (RAT).
tt; O88926           CL3AC - RATTUS NORVEGICUS (RAT).
tt; O88925           CL3AB - RATTUS NORVEGICUS (RAT).
tt; O88924           CL3AA - RATTUS NORVEGICUS (RAT).
tt; CD97_HUMAN       LEUCOCYTE ANTIGEN CD97 PRECURSOR - HOMO SAPIENS (HUMAN).
tt; O00718           CD97 - HOMO SAPIENS (HUMAN).
bb;
bb;
sh; SCAN HISTORY
sh; ------------
dn; OWL17_0     1    50 NSINGLE
dn; OWL18_0     1    50 NSINGLE
dn; OWL19_1     1    50 NSINGLE
dn; OWL20_1     1    50 NSINGLE
dn; OWL21_1     1   100 NSINGLE
dn; OWL23_2     2   100 NSINGLE
dn; OWL28_0     1   200 NSINGLE
dn; SPTR37_9f   3    80 NSINGLE
bb;
bb;
im; INITIAL MOTIF-SETS
im; ------------------
ic; GPCRSECRETIN1
il; 25
it; Secretin motif I - 1
id; MIYTVGYSMSLASLTVAVLILAYFR          PTRR_RAT    189   189
id; MIYTVGYSISLGSLTVAVLILGYFR        PTRR_DIDMA    186   186
id; VMYTVGYSSSLAMLLVALSILCSFR          SCRC_RAT    144   144
id; YLAIVGHSLSIFTLVISLGIFVFFR        CALR_HUMAN    150   150
bb;
ic; GPCRSECRETIN2
il; 25
it; Secretin motif II - 1
id; YIHMHMFLSFMLRAASIFVKDAVLY          PTRR_RAT    221     7
id; YIHMHLFVSFMLRAVSIFIKDAVLY        PTRR_DIDMA    218     7
id; YIHMHLFVSFILRALSNFIKDAVLF          SCRC_RAT    176     7
id; TLHKNMFLTYILNSMIIIIHLVEVV        CALR_HUMAN    198    23
bb;
ic; GPCRSECRETIN3
il; 24
it; Secretin motif III - 1
id; VAVTFFLYFLATNYYWILVEGLYL           PTRR_RAT    283    37
id; VAVTVFLYFLTTNYYWILVEGLYL         PTRR_DIDMA    277    34
id; LVMIFFQYCIMANYAWLLVEGLYL           SCRC_RAT    217    16
id; ILHFFHQYMMACNYFWMLCEGIYL         CALR_HUMAN    237    14
bb;
ic; GPCRSECRETIN4
il; 26
it; Secretin motif IV - 1
id; LWGFTIFGWGLPAVFVAVWVGVRATL         PTRR_RAT    321    14
id; LWGFTLFGWGLPAVFVAVWVTVRATL       PTRR_DIDMA    315    14
id; LQAFVLLGWGSPAIFVALWAITRHFL         SCRC_RAT    255    14
id; LRWYYLLGWGFPLVPTTIHAITRAVY       CALR_HUMAN    275    14
bb;
ic; GPCRSECRETIN5
il; 26
it; Secretin motif V - 1
id; WIIQVPILASVVLNFILFINIIRVLA         PTRR_RAT    361    14
id; WIIQVPILAAIVVNFILFINIIRVLA       PTRR_DIDMA    355    14
id; WVIRGPVILSILINFIFFINILRILM         SCRC_RAT    296    15
id; YIIHGPVMAALVVNFFFLLNIVRVLV       CALR_HUMAN    315    14
bb;
ic; GPCRSECRETIN6
il; 21
it; Secretin motif VI - 1
id; LLRSTLVLVPLFGVHYTVFMA              PTRR_RAT    406    19
id; LLKSTLVLMPLFGVHYIVFMA            PTRR_DIDMA    400    19
id; LAKSTLLLIPLFGIHYIVFAF              SCRC_RAT    340    18
id; AVKATMILVPLLGIQFVVFPW            CALR_HUMAN    357    16
bb;
ic; GPCRSECRETIN7
il; 22
it; Secretin motif VII - 1 
id; MHYEMLFNSFQGFFVAIIYCFC             PTRR_RAT    441    14
id; MHYEMLFNSFQGFFVAIIYCFC           PTRR_DIDMA    435    14
id; LFFELALGSFQGLVVAVLYCFL             SCRC_RAT    370     9
id; DYVMHSLIHFQGFFVATIYCFC           CALR_HUMAN    389    11
bb;
fm; FINAL MOTIF-SETS
fm; ----------------
fc; GPCRSECRETIN1
fl; 25
ft; Secretin motif I - 3
fd; TGYTIGYSLSLASLLVAMAILSLFR          VIPR_RAT    145   145
fd; VMYTVGYSSSLAMLLVALSILCSFR          SCRC_RAT    144   144
fd; VMYTVGYSSSLVMLLVALGILCAFR        SCRC_HUMAN    144   144
fd; ALYTVGYSTSLATLTTAMVILCRFR          PACR_RAT    154   154
fd; ALYTVGYSTSLVTLTTAMVILCRFR        PACR_MOUSE    155   155
fd; ALYTVGYSTSLVTLTTAMVILCRFR        PACR_HUMAN    155   155
fd; ALYTVGYSTSLVSLTTAMVILCRFR            O73769    147   147
fd; ALYTVGYSTSLVTLTTAMVILCRFR        PACR_BOVIN    172   172
fd; VMYTVGYSSSLVMLLVALGILCAFR        SCRC_RABIT    140   140
fd; TGYTIGYGLSLATLLVATAILSLFR        VIPR_HUMAN    144   144
fd; TGYTIGYSLSLAALLVATAILSLFR          VIPR_PIG    145   145
fd; AIYTLGYSVSLMSLATGSIILCLFR        VIPS_HUMAN    128   128
fd; MIYTVGYSVSLASLTVAVLILAYFR        PTRR_HUMAN    189   189
fd; MIYTVGYSISLGSLTVAVLILGYFR        PTRR_DIDMA    186   186
fd; MIYTVGYSVSLASLTVAVLILAYFR          PTRR_PIG    185   185
fd; IGYTIGHSVSLISLTTAIVILCMSR        VIPR_CARAU    105   105
fd; AIYTLGYSVSLMSLTTGSIIICLFR        VIPS_MOUSE    127   127
fd; AIYTLGYSVSLMSLTTGSIIICLFR          VIPS_RAT    127   127
fd; MIYTVGYSMSLASLTVAVLILAYFR        PTRR_MOUSE    189   189
fd; MIYTVGYSMSLASLTVAVLILAYFR          PTRR_RAT    189   189
fd; QLYTAGYATSLISLITAVIIFTCFR            O73768    138   138
fd; VVYTVGYSLSLATLLLALLILSLFR          GIPR_RAT    136   136
fd; VMYTVGYSLSLATLLLALLILSLFR        GIPR_HUMAN    139   139
fd; VVYTVGYSLSLGTLLLALLILSLFR        GIPR_MESAU    136   136
fd; VMYTVGYSLSLGALLLALVILLGLR           GLR_RAT    144   144
fd; IIYTVGYALSFSALVIASAILVSFR          GLPR_RAT    146   146
fd; VMYTVGYSLSLGALLLALVILLGLR         GLR_MOUSE    144   144
fd; IIYTVGYALSFSALVIASAILVGFR        GLPR_MOUSE    146   146
fd; VMYTVGYSLSLGALLLALAILGGLS         GLR_HUMAN    143   143
fd; IIYTVGYALSFSALVIASAILLGFR        GLPR_HUMAN    146   146
fd; IINYLGHCISLVALLVAFVLFLRLR        CRFR_MOUSE    121   121
fd; IINYLGHCISLAALLVAFVLFLRLR        CRFR_SHEEP    121   121
fd; IINYLGHCISLVALLVAFVLFLRLR        CRFR_HUMAN    121   121
fd; IINYLGHCISLVALLVAFVLFLRLR          CRFR_RAT    121   121
fd; VINFLGHSISLCALLVAFILFLRLR        CRFR_XENLA    121   121
fd; IINYLGHCVSVVALVAAFLLFLVLR          CRF2_RAT    118   118
fd; VMYTVGYSISFGSLAVAILIIGYFR        PTR2_HUMAN    146   146
fd; IVYTTGHSVSAVALFVAIAILVALR          GRFR_PIG    131   131
fd; VVNYLGHCVSVAALVAAFLLFLALR            Q99431    145   145
fd; VVNYLGHCVSVAALVAAFLLFLALR            O43461    104   104
fd; VVNYLGHCVSVAALVAAFLLFLALR        CRF2_HUMAN    118   118
fd; IIYTVGHSISIVALFVAITILVALR        GRFR_HUMAN    131   131
fd; ILYTVGYSISFGSLAVAILIIGYFR          PTH2_RAT    144   144
fd; IIYTTGHSISIVALCVAIAILVALR          GRFR_RAT    131   131
fd; IVNYLGHCVSVVALVAAFLLFLVLR        CRF2_MOUSE    138   138
fd; IIYTTGHSISIVALCVAIAILVALR        GRFR_MOUSE    131   131
fd; IINYLGHCVSLGTLLVAFVLFMRLR        CRFR_CHICK    126   126
fd; IINYLGHCISILALVIAFLLFLCLR        CRF2_XENLA    120   120
fd; YLAIVGHSMSIITLVVSLGIFVYFR        CALR_CAVPO    150   150
fd; YLAIVGHSLSIFTLVISLGIFVFFR        CALR_HUMAN    150   150
fd; YLAIVGHSLSIFTLVISLGIFKCFR        CALR_RABIT    150   150
fd; YLALVGHSMSIAALIASMGIFLFFK          CALR_RAT    150   150
fd; YLALVGHSLSIAALVASMLIFWIFK        CALR_MOUSE    150   150
fd; YLAIVGHSLSILTLLISLGIFMFLR          CALR_PIG    151   151
fd; LIYLAGYSLSLAVLSLAVFVFLYFK        DIHR_MANSE     88    88
fd; YLTIIGHGLSIASLLISLGIFFYFK        CGRR_HUMAN    143   143
fd; YLTIIGHGLSIASLIISLIIFFYFK          CGRR_RAT    143   143
fd; FVFFVGFCLSLVAIAVAIWIFLYFK        DIHR_ACHDO    135   135
fd; SVSLTLSFVSVILLVAAIVLFSIFD            Q93245     40    40
bb;
fc; GPCRSECRETIN2
fl; 25
ft; Secretin motif II - 3
fd; YIHMHLFMSFILRATAVFIKDMALF          VIPR_RAT    177     7
fd; YIHMHLFVSFILRALSNFIKDAVLF          SCRC_RAT    176     7
fd; YIHMHLFVSFILRALSNFIKDAVLF        SCRC_HUMAN    176     7
fd; FIHMNLFVSFMLRAISVFIKDWILY          PACR_RAT    186     7
fd; FIHMNLFVSFMLRAISVFIKDWILY        PACR_MOUSE    187     7
fd; FIHMNLFVSFMLRAISVFIKDWILY        PACR_HUMAN    187     7
fd; FIHMNLFVSFMLRAISVFIKDGVLY            O73769    179     7
fd; FIHMNLFVSFMLRAISVFIKDWILY        PACR_BOVIN    204     7
fd; YIHMHLFLSFILRALSNFIKDAVLF        SCRC_RABIT    172     7
fd; YIHMHLFISFILRAAAVFIKDLALF        VIPR_HUMAN    176     7
fd; YIHMHLFISFILRATAVFIKDLALF          VIPR_PIG    177     7
fd; YIHLNLFLSFILRAISVLVKDDVLY        VIPS_HUMAN    160     7
fd; YIHMHLFLSFMLRAVSIFVKDAVLY        PTRR_HUMAN    221     7
fd; YIHMHLFVSFMLRAVSIFIKDAVLY        PTRR_DIDMA    218     7
fd; YIHMHLFLSFMLRAVSIFVKDAVLY          PTRR_PIG    217     7
fd; YIHMHLFVSFILKAIAVFVKDAVLY        VIPR_CARAU    137     7
fd; YIHLNLFLSFMLRAISVLVKDSVLY        VIPS_MOUSE    159     7
fd; YIHLNLFLSFMLRAISVLVKDSVLY          VIPS_RAT    159     7
fd; YIHMHMFLSFMLRAASIFVKDAVLY        PTRR_MOUSE    221     7
fd; YIHMHMFLSFMLRAASIFVKDAVLY          PTRR_RAT    221     7
fd; YIHINLFVSFILRATAVFIKDAVLF            O73768    170     7
fd; YIHMNLFTSFMLRAGAILTRDQLLP          GIPR_RAT    168     7
fd; YIHINLFTSFMLRAAAILSRDRLLP        GIPR_HUMAN    171     7
fd; YIHMNVFLSFMLRAVAILTRDRLLP        GIPR_MESAU    168     7
fd; YIHGNLFASFVLKAGSVLVIDWLLK           GLR_RAT    176     7
fd; YIHLNLFASFILRALSVFIKDAALK          GLPR_RAT    178     7
fd; YIHGNLFASFVLKAGSVLVIDWLLK         GLR_MOUSE    176     7
fd; YIHLNLFASFILRALSVFIKDAALK        GLPR_MOUSE    178     7
fd; AIHANLFASFVLKASSVLVIDGLLR         GLR_HUMAN    175     7
fd; YIHLNLFASFILRALSVFIKDAALK        GLPR_HUMAN    178     7
fd; IIHWNLISAFILRNATWFVVQLTVS        CRFR_MOUSE    153     7
fd; IIHWNLISAFILRNATWFVVQLTMS        CRFR_SHEEP    153     7
fd; IIHWNLISAFILRNATWFVVQLTMS        CRFR_HUMAN    182    36
fd; IIHWNLISAFILRNATWFVVQLTVS          CRFR_RAT    153     7
fd; IIHWNLITAFILRNVTWFVMQLTLS        CRFR_XENLA    153     7
fd; VIHWNLITTFILRNITWFLLQLIDH          CRF2_RAT    150     7
fd; YIHMHLFVSFMLRATSIFVKDRVVH        PTR2_HUMAN    178     7
fd; YIHSQLFATFILKAGAVFLKDAALF          GRFR_PIG    163     7
fd; VIHWNLITTFILRNVMWFLLQLVDH            Q99431    177     7
fd; VIHWNLITTFILRNVMWFLLQLVDH            O43461    136     7
fd; VIHWNLITTFILRNVMWFLLQLVDH        CRF2_HUMAN    150     7
fd; YVHTQLFTTFILKAGAVFLKDAALF        GRFR_HUMAN    163     7
fd; YIHLHLFVSFMLRAXSIFVKDRVAQ          PTH2_RAT    176     7
fd; YIHTQLFATFILKASAVFLKDAAVF          GRFR_RAT    163     7
fd; VIHWNLITTFILRNIAWFLLQLIDH        CRF2_MOUSE    170     7
fd; YIHTQLFATFILKASAVFLKDAAIF        GRFR_MOUSE    163     7
fd; IIHWNLITAFILRNATWFVVQLTMN        CRFR_CHICK    158     7
fd; IIHWNLITTFILRNIMWFLLQMIDH        CRF2_XENLA    152     7
fd; TLHKNMFLTYILNSMIIIIHLVEVV        CALR_CAVPO    182     7
fd; TLHKNMFLTYILNSMIIIIHLVEVV        CALR_HUMAN    198    23
fd; TLHKNMFLTYILNSMIIIIHLVEVV        CALR_RABIT    182     7
fd; TLHKNMFLTYILNSIIIIIHLVEVV          CALR_RAT    182     7
fd; TLHKHMFLTYILNSIIIIIHLVEVV        CALR_MOUSE    182     7
fd; TLHKNMFLTYVLNSIIIIVHLVVIV          CALR_PIG    199    23
fd; TIHTNLMSTYILSACSWILNLVLQN        DIHR_MANSE    120     7
fd; TLHKNLFFSFVCNSVVTIIHLTAVA        CGRR_HUMAN    175     7
fd; TLHKNLFFSFVCNSIVTIIHLTAVA          CGRR_RAT    175     7
fd; TIHTNLMATYICNDATWIISAVVQE        DIHR_ACHDO    167     7
fd; SIHKNLATAFVFRFAVLAIWTIVQT            Q93245     91    26
bb;
fc; GPCRSECRETIN3
fl; 24
ft; Secretin motif III - 3
fd; AAVVFFQYCVMANFFWLLVEGLYL           VIPR_RAT    218    16
fd; LVMIFFQYCIMANYAWLLVEGLYL           SCRC_RAT    217    16
fd; LVMVLFQYCIMANYSWLLVEGLYL         SCRC_HUMAN    217    16
fd; AVMVFFHYCVVSNYFWLFIEGLYL           PACR_RAT    227    16
fd; AVMVFFHYCVVSNYFWLFIEGLYL         PACR_MOUSE    228    16
fd; AVMVFFHYCVVSNYFWLFIEGLYL         PACR_HUMAN    228    16
fd; AVMVFFHYCVMSNYFWLFIEGLYL             O73769    220    16
fd; AVMVFFHYCVVSNYFWLFIEGLYL         PACR_BOVIN    245    16
fd; LVMVFFQYCIMANYAWLLVEGLYL         SCRC_RABIT    213    16
fd; AAMVFFQYCVMANFFWLLVEGLYL         VIPR_HUMAN    217    16
fd; AAVVLFQYCVMANFFWLLVEGLYL           VIPR_PIG    218    16
fd; LSLVFLQYCIMANFFWLLVEGLYL         VIPS_HUMAN    204    19
fd; VAVTFFLYFLATNYYWILVEGLYL         PTRR_HUMAN    283    37
fd; VAVTVFLYFLTTNYYWILVEGLYL         PTRR_DIDMA    277    34
fd; VAVTFFLYFLATNYYWILVEGLYL           PTRR_PIG    278    36
fd; AVIVFFQYCIMASFFWLLVEGLYL         VIPR_CARAU    179    17
fd; LSLVFFQYCIMANFYWLLVEGLYL         VIPS_MOUSE    203    19
fd; LSLVFFQYCIMANFYWLLVEGLYL           VIPS_RAT    203    19
fd; VAVTFFLYFLATNYYWILVEGLYL         PTRR_MOUSE    283    37
fd; VAVTFFLYFLATNYYWILVEGLYL           PTRR_RAT    283    37
fd; TAVTFFQFCILTNYFWLLVEGLYL             O73768    211    16
fd; TAQILTQYCVGANYTWLLVEGVYL           GIPR_RAT    215    22
fd; TAQIVTQYCVGANYTWLLVEGVYL         GIPR_HUMAN    218    22
fd; TAQIVTQYCVGANYTWLLVEGVYL         GIPR_MESAU    215    22
fd; VATVIMQYGIIANYCWLLVEGVYL            GLR_RAT    227    26
fd; LVFLLMQYCVAANYYWLLVEGVYL           GLPR_RAT    228    25
fd; VATVIMQYGIIPNYCWLLVEGVYL          GLR_MOUSE    227    26
fd; LVFLLMQYCVAANYYWLLVEGVYL         GLPR_MOUSE    228    25
fd; VAAVFMQYGIVANYCWLLVEGLYL          GLR_HUMAN    226    26
fd; LVFLLMQYCVAANYYWLLVEGVYL         GLPR_HUMAN    228    25
fd; LVTAAYNYFHVTNFFWMFGEGCYL         CRFR_MOUSE    190    12
fd; LVTAAYNYFHVTNFFWMFGEGCYL         CRFR_SHEEP    190    12
fd; LVTAAYNYFHVTNFFWMFGEGCYL         CRFR_HUMAN    219    12
fd; LVTAAYNYFHVTNFFWMFGEGCYL           CRFR_RAT    190    12
fd; LVTIAHNYFYVTNFFWMFGEGCYL         CRFR_XENLA    190    12
fd; CVTTIFNYFVVTNFFWMFVEGCYL           CRF2_RAT    186    11
fd; IAVVMFIYFLATNYYWILVEGLYL         PTR2_HUMAN    238    35
fd; VSVATSHFATMTNFSWLLAEAVYL           GRFR_PIG    204    16
fd; CITTIFNYFVVTNFFWMFVEGCYL             Q99431    213    11
fd; CITTIFNYFVVTNFFWMFVEGCYL             O43461    172    11
fd; CITTIFNYFVVTNFFWMFVEGCYL         CRF2_HUMAN    186    11
fd; VSVAASHFATMTNFSWLLAEAVYL         GRFR_HUMAN    204    16
fd; IAVVMFIYFLATNYYWILVEGLYL           PTH2_RAT    236    35
fd; VSVAVSHFATMTNFSWLLAEAVYL           GRFR_RAT    204    16
fd; CITTIFNYFVVTNFFWMFVEGCYL         CRF2_MOUSE    206    11
fd; VSVAISHLATMTNFSWLLAEAVYL         GRFR_MOUSE    204    16
fd; LVTAAYNYFHVTNFFWMFGEGCYL         CRFR_CHICK    195    12
fd; CITTIYNYFVVTNFFWMFVEGCYL         CRF2_XENLA    188    11
fd; ILHFFHQYMMACNYFWMLCEGIYL         CALR_CAVPO    221    14
fd; ILHFFHQYMMACNYFWMLCEGIYL         CALR_HUMAN    237    14
fd; VLHFFHQYMMSCNYFWMLCEGIYL         CALR_RABIT    221    14
fd; ILHFFHQYMMACNYFWMLCEGIYL           CALR_RAT    258    51
fd; VLHFLHQYMMSCNYFWMLCEGIYL         CALR_MOUSE    258    51
fd; VLHFFHQYMMSCNYFWMLCEGVYL           CALR_PIG    238    14
fd; ILVICMNYFYLTNFFWMLVEGLYL         DIHR_MANSE    158    13
fd; VSQFIHLYLMGCNYFWMLCEGIYL         CGRR_HUMAN    214    14
fd; VSQFIHLYLMGCNYFWMLCEGIYL           CGRR_RAT    214    14
fd; VLAVLMHYFYLTNFFWMFVEGLYL         DIHR_ACHDO    201     9
fd; AILWFVIYFNVASVMWMLIEGAFL             Q93245    139    23
bb;
fc; GPCRSECRETIN4
fl; 26
ft; Secretin motif IV - 3
fd; FWGYILIGWGVPSVFITIWTVVRIYF         VIPR_RAT    256    14
fd; LQAFVLLGWGSPAIFVALWAITRHFL         SCRC_RAT    255    14
fd; LQGFVAFGWGSPAIFVALWAIARHFL       SCRC_HUMAN    255    14
fd; FYWYTIIGWGTPTVCVTVWAVLRLYF         PACR_RAT    265    14
fd; FYWYTIIGWGTPTVCVTVWAVLRLYF       PACR_MOUSE    266    14
fd; FYWYTIIGWGTPTVCVTVWATLRLYF       PACR_HUMAN    266    14
fd; FYWYTIIGWGTPTICVTIWAVLRLHF           O73769    258    14
fd; FYWYIIIGWGTPTVCVSVWAMLRLYF       PACR_BOVIN    283    14
fd; LQGFVVLGWGSPAMFVTSWAVTRHFL       SCRC_RABIT    251    14
fd; FWGYILIGWGVPSTFTMVWTIARIHF       VIPR_HUMAN    255    14
fd; FWGYIFVGWGVPSTFIMVWTVVRIHF         VIPR_PIG    256    14
fd; FLAYLLIGWGLPTVCIGAWTAARLYL       VIPS_HUMAN    241    13
fd; LWGFTVFGWGLPAVFVAVWVSVRATL       PTRR_HUMAN    321    14
fd; LWGFTLFGWGLPAVFVAVWVTVRATL       PTRR_DIDMA    315    14
fd; LWGFTVFGWGLPAIFVAVWVSVRATL         PTRR_PIG    316    14
fd; FWWYILIGWGGPTIFIMAWSFAKAYF       VIPR_CARAU    217    14
fd; FLAYLLIGWGIPSVCIGAWTATRLSL       VIPS_MOUSE    240    13
fd; FLAYLLIGWGIPSVCIGAWIATRLSL         VIPS_RAT    240    13
fd; LWGFTIFGWGLPAVFVAVWVGVRATL       PTRR_MOUSE    321    14
fd; LWGFTIFGWGLPAVFVAVWVGVRATL         PTRR_RAT    321    14
fd; FWWYILIGWGVPSVVLIVWVLTRQFY           O73768    249    14
fd; FRCYLLLGWGAPALFVIPWVIVRYLY         GIPR_RAT    253    14
fd; FRYYLLLGWGAPALFVIPWVIVRYLY       GIPR_HUMAN    256    14
fd; FRCYLLLGWGAPALFVIPWVIVRYLL       GIPR_MESAU    253    14
fd; FSLYLCIGWGSPLLFVIPWVVVKCLF          GLR_RAT    265    14
fd; FKLYLSIGWGVPLLFVIPWGIVKYLY         GLPR_RAT    266    14
fd; FSLYLGIGWGAPLLFVIPWVVVKCLF        GLR_MOUSE    265    14
fd; FKLYLSIGWGVPLLFVIPWGIVKYLY       GLPR_MOUSE    266    14
fd; FSLYLGIGWGAPMLFVVPWAVVKCLF        GLR_HUMAN    264    14
fd; FRLYVSIGWGVPLLFVVPWGIVKYLY       GLPR_HUMAN    266    14
fd; KWMFVCIGWGVPFPIIVAWAIGKLYY       CRFR_MOUSE    228    14
fd; KWMFICIGWGVPFPIIVAWAIGKLYY       CRFR_SHEEP    228    14
fd; KWMFICIGWGVPFPIIVAWAIGKLYY       CRFR_HUMAN    257    14
fd; KWMFVCIGWGVPFPIIVAWAIGKLHY         CRFR_RAT    228    14
fd; KWMFICIGWCIPFPIIVAWAIGKLYY       CRFR_XENLA    228    14
fd; KWLFLFIGWCIPCPIIVAWAVGKLYY         CRF2_RAT    224    14
fd; LWGFILIGWGFPAAFVAAWAVARATL       PTR2_HUMAN    276    14
fd; FWWLVLAGWGLPLLFTGTWVGCKLAF         GRFR_PIG    242    14
fd; KCLFLFIGWCIPFPIIVAWAIGKLYY           Q99431    251    14
fd; KCLFLFIGWCIPFPIIVAWAIGKLYY           O43461    210    14
fd; KCLFLFIGWCIPFPIIVAWAIGKLYY       CRF2_HUMAN    224    14
fd; FWWLVLAGWGLPVLFTGTWVSCKLAF       GRFR_HUMAN    242    14
fd; LWGFILIGWGFPAVFVVAWAVARATL         PTH2_RAT    274    14
fd; FWWLVLAGWGLPVLCTGTWVGCKLAF         GRFR_RAT    242    14
fd; KWLFLFIGWCIPCPIIIAWAVGKLYY       CRF2_MOUSE    244    14
fd; FWWLVLAGWGLPVLCTGTWVGCKHSF       GRFR_MOUSE    242    14
fd; KWMFICIGWCIPFPIIVAWAIGKLYY       CRFR_CHICK    233    14
fd; KWVFLFIGWCIPSPIIVTWAICKLFY       CRF2_XENLA    226    14
fd; LRWYYLLGWGFPLVPTTIHAITRALY       CALR_CAVPO    259    14
fd; LRWYYLLGWGFPLVPTTIHAITRAVY       CALR_HUMAN    275    14
fd; LRWYYLLGWGFPLVPTTIHAITRAIY       CALR_RABIT    259    14
fd; LRWYYLLGWGFPIVPTIIHAITRAVY         CALR_RAT    296    14
fd; LRWYYLLGWGFPIVPTIIHAITRALY       CALR_MOUSE    296    14
fd; LWWYHVLGWGFPLIPTTAHAITRAVL         CALR_PIG    276    14
fd; LKVYTTIGWGAPAVFITIWVISRCFV       DIHR_MANSE    196    14
fd; LMWYYFLGWGFPLIPACIHAIARSLY       CGRR_HUMAN    252    14
fd; LMWYYFLGWGFPLLPACIHAIARSLY         CGRR_RAT    252    14
fd; LQIYIIIGWGIPGVIVVTWAIIKHLG       DIHR_ACHDO    239    14
fd; WSLYLACGWGVPFVVVTAWALVHQYI           Q93245    178    15
bb;
fc; GPCRSECRETIN5
fl; 26
ft; Secretin motif V - 3
fd; WIIKAPILLSILVNFVLFICIIRILV         VIPR_RAT    297    15
fd; WVIRGPVILSILINFIFFINILRILM         SCRC_RAT    296    15
fd; WIIRGPVILSILINFILFINILRILM       SCRC_HUMAN    296    15
fd; WVIKGPVVGSIMVNFVLFIGIIIILV         PACR_RAT    306    15
fd; WVIKGPVVGSIMVNFVLFIGIIIILV       PACR_MOUSE    307    15
fd; WVIKGPVVGSIMVNFVLFIGIIVILV       PACR_HUMAN    307    15
fd; WVIKGPVVASIMINFVLFIGIIIILV           O73769    299    15
fd; WVIKGPVVGSIMVNFVLFIGIIVILV       PACR_BOVIN    324    15
fd; WVIRGPVILSILINFILFINILRILT       SCRC_RABIT    292    15
fd; WIIKGPILTSILVNFILFICIIRILL       VIPR_HUMAN    295    14
fd; WIIKAPILASILVNFILFIRIIGILV         VIPR_PIG    296    14
fd; WVIRIPILISIIVNFVLFISIIRILL       VIPS_HUMAN    282    15
fd; WIIQVPILASIVLNFILFINIVRVLA       PTRR_HUMAN    361    14
fd; WIIQVPILAAIVVNFILFINIIRVLA       PTRR_DIDMA    355    14
fd; WIIQVPILASIVLNFILFINIVRVLA         PTRR_PIG    356    14
fd; WIIKTPILASILMNFILFICIIRILR       VIPR_CARAU    259    16
fd; WVIRMPILISIVVNFALFISIVRILL       VIPS_MOUSE    281    15
fd; WVIRMPILISIVVNFALFISIVRILL         VIPS_RAT    281    15
fd; WIIQVPILASVVLNFILFINIIRVLA       PTRR_MOUSE    361    14
fd; WIIQVPILASVVLNFILFINIIRVLA         PTRR_RAT    361    14
fd; WIIKGPITVSLIANIIIFLNVIRILV           O73768    290    15
fd; WIIRTPILITILINFLIFIRILGILV         GIPR_RAT    294    15
fd; WIIRTPILMTILINFLIFIRILGILL       GIPR_HUMAN    297    15
fd; WIIRTPILITILINFFIFIRILGILV       GIPR_MESAU    294    15
fd; WILRIPVLLAILINFFIFVRIIHLLV          GLR_RAT    306    15
fd; LIIRLPILFAIGVNFLVFIRVICIVI         GLPR_RAT    307    15
fd; WILRIPVFLALLINFFIFVHIIQLLV        GLR_MOUSE    306    15
fd; LIIRLPILFAIGVNFLIFIRVICIVV       GLPR_MOUSE    307    15
fd; WILRFPVFLAILINFFIFVRIVQLLV        GLR_HUMAN    305    15
fd; LIIRLPILFAIGVNFLIFVRVICIVV       GLPR_HUMAN    307    15
fd; YIYQGPMILVLLINFIFLFNIVRILM       CRFR_MOUSE    270    16
fd; YIYQGPMILVLLINFIFLFNIVRILM       CRFR_SHEEP    270    16
fd; YIYQGPMILVLLINFIFLFNIVRILM       CRFR_HUMAN    299    16
fd; YIYQGPMILVLLINFIFLFNIVRILM         CRFR_RAT    270    16
fd; FIYQGPVILVLLINFIFLFNIVRILM       CRFR_XENLA    270    16
fd; YIYQGPIILVLLINFVFLFNIVRILM         CRF2_RAT    266    16
fd; WIYQAPILAAIGLNFILFLNTVRVLA       PTR2_HUMAN    316    14
fd; WIIKGPIVLSVGVNFGLFLNIIRILL         GRFR_PIG    283    15
fd; YIYQGPIILVLLINFVFLFNIVRILM           Q99431    293    16
fd; YIYQGPIILVLLINFVFLFNIVRILM           O43461    252    16
fd; YIYQGPIILVLLINFVFLFNIVRILM       CRF2_HUMAN    266    16
fd; WIIKGPIVLSVGVNFGLFLNIIRILV       GRFR_HUMAN    283    15
fd; WIYXXPILAAIGLNFILFLNTVRVLA         PTH2_RAT    313    13
fd; WIIKGPIVLSVGVNFGLFLNIICILL         GRFR_RAT    283    15
fd; YIYQGPVMLVLLINFVFLFNIVRILM       CRF2_MOUSE    286    16
fd; WIIKGPIVLSVGVNFGLFLNIICILL       GRFR_MOUSE    283    15
fd; YIYQGPMILVLLINFIFLFNIVRILM       CRFR_CHICK    275    16
fd; YIYQGRVILVLLINFVFLFNIVRILM       CRF2_XENLA    268    16
fd; YIIHGPVMVALVVNFFFLLNIVRVLV       CALR_CAVPO    299    14
fd; YIIHGPVMAALVVNFFFLLNIVRVLV       CALR_HUMAN    315    14
fd; YIIHGPVMAALVVNFFFLLNIVRVLV       CALR_RABIT    299    14
fd; YIIHGPVMAALVVNFFFLLNIVRVLV         CALR_RAT    336    14
fd; YIIHGPVMVALVVNFFFLLNIVRVLV       CALR_MOUSE    336    14
fd; YIIHGPVMAALVVNFFFLLNILRVLV         CALR_PIG    316    14
fd; WIHKAPALVGLALNLFFLIRIMWVLI       DIHR_MANSE    251    29
fd; YIIHGPICAALLVNLFFLLNIVRVLI       CGRR_HUMAN    292    14
fd; YIIHGPICAALLVNLFFLLNIVRVLI         CGRR_RAT    292    14
fd; WIHQAPVITVLAVNLVFLFSIMWVLI       DIHR_ACHDO    294    29
fd; WILAGTMGSALIMNLIFLLMIVVILV           Q93245    223    19
bb;
fc; GPCRSECRETIN6
fl; 21
ft; Secretin motif VI - 3
fd; LAKSTLLLIPLFGIHYVMFAF              VIPR_RAT    341    18
fd; LAKSTLLLIPLFGIHYIVFAF              SCRC_RAT    340    18
fd; LARSTLLLIPLFGIHYIVFAF            SCRC_HUMAN    340    18
fd; LARSTLLLIPLFGIHYTVFAF              PACR_RAT    406    74
fd; LARSTLLLIPLFGIHYTVFAF            PACR_MOUSE    379    46
fd; LARSTLLLIPLFGIHYTVFAF            PACR_HUMAN    351    18
fd; LARSTLLLIPLFGIHYTVFAF                O73769    343    18
fd; LARSTLLLIPLFGIHYTVFAF            PACR_BOVIN    396    46
fd; LARSTLLLIPLFGVHYIVFVF            SCRC_RABIT    336    18
fd; LARSTLLLIPLFGVHYIMFAF            VIPR_HUMAN    339    18
fd; LAKSTLLLIPLFGVHYIMFAF              VIPR_PIG    340    18
fd; LAKSTLLLIPLFGVHYMVFAV            VIPS_HUMAN    326    18
fd; LLKSTLVLMPLFGVHYIVFMA            PTRR_HUMAN    406    19
fd; LLKSTLVLMPLFGVHYIVFMA            PTRR_DIDMA    400    19
fd; LLKSTLVLMPLFGVHYIVFMA              PTRR_PIG    401    19
fd; LAKSTLLLIPLFGINFIIFAF            VIPR_CARAU    303    18
fd; LAKSTLLLIPLFGVHYMVFAA            VIPS_MOUSE    325    18
fd; LAKSTLLLIPLFGVHYMVFAA              VIPS_RAT    325    18
fd; LLRSTLVLVPLFGVHYTVFMA            PTRR_MOUSE    406    19
fd; LLRSTLVLVPLFGVHYTVFMA              PTRR_RAT    406    19
fd; LAKSTLFLIPLFGMHYTLFAF                O73768    334    18
fd; LARSTLTLMPLLGVHEVVFAP              GIPR_RAT    336    16
fd; LARSTLTLVPLLGVHEVVFAP            GIPR_HUMAN    339    16
fd; LARSTLTLVPLLGVHEVVFAP            GIPR_MESAU    336    16
fd; LARSTLTLIPLLGVHEVVFAF               GLR_RAT    348    16
fd; LAKSTLTLIPLLGTHEVIFAF              GLPR_RAT    349    16
fd; LARSTLTLIPLLGVHEVVFAF             GLR_MOUSE    348    16
fd; LAKSTLTLIPLLGTHEVIFAF            GLPR_MOUSE    349    16
fd; LAKSTLTLIPLLGVHEVVFAF             GLR_HUMAN    347    16
fd; LAKSTLTLIPLLGTHEVIFAF            GLPR_HUMAN    349    16
fd; AVKATLVLLPLLGITYMLFFV            CRFR_MOUSE    312    16
fd; AVKATLVLLPLLGITYMLFFV            CRFR_SHEEP    312    16
fd; AVKATLVLLPLLGITYMLFFV            CRFR_HUMAN    341    16
fd; AVKATLVLLPLLGITYMLFFV              CRFR_RAT    312    16
fd; AVKATLVLLPLLGITYMLFFV            CRFR_XENLA    312    16
fd; AVKATLVLLPLLGITYMLFFV              CRF2_RAT    308    16
fd; LAKSTLVLVLVFGVHYIVFVC            PTR2_HUMAN    361    19
fd; LSKSTLLLIPLFGIHYVIFNF              GRFR_PIG    327    18
fd; AVKATLVLLPLLGITYMLFFV                Q99431    335    16
fd; AVKATLVLLPLLGITYMLFFV                O43461    294    16
fd; AVKATLVLLPLLGITYMLFFV            CRF2_HUMAN    308    16
fd; LSKSTLFLIPLFGIHYIIFNF            GRFR_HUMAN    327    18
fd; LAKSTLVLVLVFGVHYIVFIC              PTH2_RAT    358    19
fd; LSKSTLLLIPLFGIHYIIFNF              GRFR_RAT    368    59
fd; AVKATLVLLPLLGITYMLFFV            CRF2_MOUSE    328    16
fd; LSKSTLLLIPLFGIHYIIFNF            GRFR_MOUSE    327    18
fd; AVKATLVLLSLLGITYMLFFV            CRFR_CHICK    317    16
fd; AVKATLVLLPLLGITYMLFFV            CRF2_XENLA    310    16
fd; AVKATMILVPLLGIQFVVFPW            CALR_CAVPO    341    16
fd; AVKATMILVPLLGIQFVVFPW            CALR_HUMAN    357    16
fd; AVKATMILVPLLGIQFVVFPW            CALR_RABIT    341    16
fd; AVKATMVLVPLLGIQFVVFPW              CALR_RAT    378    16
fd; AVKATMVLVPLLGIQFVVFPW            CALR_MOUSE    378    16
fd; AVRATLILVPLLGVQFVVLPW              CALR_PIG    358    16
fd; ATKALLVLIPLLGITNLLVLC            DIHR_MANSE    293    16
fd; AVRATLILVPLLGIEFVLIPW            CGRR_HUMAN    334    16
fd; AVRATLILVPLLGIEFVLFPW              CGRR_RAT    334    16
fd; ATKALLVLFPLLGITYILMMQ            DIHR_ACHDO    336    16
fd; TIKATLLLVPLLGISNIPLFY                Q93245    265    16
bb;
fc; GPCRSECRETIN7
fl; 22
ft; Secretin motif VII - 3
fd; MVFELVVGSFQGFVVAILYCFL             VIPR_RAT    372    10
fd; LFFELALGSFQGLVVAVLYCFL             SCRC_RAT    370     9
fd; LFFELALGSFQGLVVAVLYCFL           SCRC_HUMAN    370     9
fd; LVFELGLGSFQGFVVAVLYCFL             PACR_RAT    437    10
fd; LVFELGLGSFQGFVVAVLYCFL           PACR_MOUSE    410    10
fd; LVFELGLGSFQGFVVAVLYCFL           PACR_HUMAN    382    10
fd; LVFELGLGSFQGFVVAVLYCFL               O73769    374    10
fd; LVFELGLGSFQGFVVAVLYCFL           PACR_BOVIN    427    10
fd; LFFELALGSFQGLVVAVLYCFL           SCRC_RABIT    366     9
fd; MVFELVVGSFQGFVVAILYCFL           VIPR_HUMAN    370    10
fd; MVFELIVGSFQGCVVAILYCFL             VIPR_PIG    371    10
fd; ILFELCLGSFQGLVVAVLYCFL           VIPS_HUMAN    357    10
fd; MHYEMLFNSFQGFFVAIIYCFC           PTRR_HUMAN    441    14
fd; MHYEMLFNSFQGFFVAIIYCFC           PTRR_DIDMA    435    14
fd; MHYEMLFNSFQGFFVAIIYCFC             PTRR_PIG    436    14
fd; LVFDLILGSFQGFVVAVLYCFL           VIPR_CARAU    334    10
fd; ILFELCVGSFQGLVVAVLYCFL           VIPS_MOUSE    356    10
fd; ILFELCVGSFQGLVVAVLYCFL             VIPS_RAT    356    10
fd; MHYEMLFNSFQGFFVAIIYCFC           PTRR_MOUSE    441    14
fd; MHYEMLFNSFQGFFVAIIYCFC             PTRR_RAT    441    14
fd; FYIELGLGSFQGFVVALLYCFL               O73768    365    10
fd; LAFEIFLSSFQGFLVSVLYCFI             GIPR_RAT    371    14
fd; LGFEIFLSSFQGFLVSVLYCFI           GIPR_HUMAN    374    14
fd; LAFEIFLSSFQGFLVSVLYCFI           GIPR_MESAU    371    14
fd; LFFDLFFSSFQGLLVAVLYCFL              GLR_RAT    383    14
fd; LFTELSFTSFQGFMVAVLYCFV             GLPR_RAT    384    14
fd; LFFDLFLSSFQGLLVAVLYCFL            GLR_MOUSE    383    14
fd; LFTELSFTSFQGLMVAILYCFV           GLPR_MOUSE    384    14
fd; LFFDLFLSSFQGLLVAVLYCFL            GLR_HUMAN    382    14
fd; LFTELSFTSFQGLMVAILYCFV           GLPR_HUMAN    384    14
fd; IYFNSFLESFQGFFVSVFYCFL           CRFR_MOUSE    345    12
fd; IYFNSFLESFQGFFVSVFYCFL           CRFR_SHEEP    345    12
fd; IYFNSFLESFQGFFVSVFYCFL           CRFR_HUMAN    374    12
fd; IYFNSFLESFQGFFVSVFYCFL             CRFR_RAT    345    12
fd; IYFNSFLQSFQGFFVSVFYCFL           CRFR_XENLA    345    12
fd; IYFNSFLQSFQGFFVSVFYCFF             CRF2_RAT    341    12
fd; MHCELFFNSFQGFFVSIIYCYC           PTR2_HUMAN    395    13
fd; LPLELGLGSFQGFIVAILYCFL             GRFR_PIG    358    10
fd; IYFNSFLQSFQGFFVSVFYCFF               Q99431    368    12
fd; IYFNSFLQSFQGFFVSVFYCFF               O43461    327    12
fd; IYFNSFLQSFQGFFVSVFYCFF           CRF2_HUMAN    341    12
fd; LPLELGLGSFQGFIVAILYCFL           GRFR_HUMAN    358    10
fd; MHCELFFNSFQGFFVSIVYCYC             PTH2_RAT    392    13
fd; LPLELGLGSFQGFVVAVLYCFL             GRFR_RAT    399    10
fd; IYFNSFLQSFQGFFVSVFYCFF           CRF2_MOUSE    361    12
fd; VPLELGLGSFQGFIVAVLYCFL           GRFR_MOUSE    358    10
fd; IYFNSFLESFQGFFVSVFYCFL           CRFR_CHICK    350    12
fd; IYFNSFLQSFQGFFVSVFYCFL           CRF2_XENLA    343    12
fd; DYFMHSLIHFQGFFVATIYCFC           CALR_CAVPO    373    11
fd; DYVMHSLIHFQGFFVATIYCFC           CALR_HUMAN    389    11
fd; DYLMHSLIHFQGFFVATIYCFC           CALR_RABIT    373    11
fd; DYLMHSLIHFQGFFVATIYCFC             CALR_RAT    410    11
fd; DYLMHSLIHFQGFFVATIYCFC           CALR_MOUSE    410    11
fd; DYVVHSLIHFQGFFVAIIYCFC             CALR_PIG    390    11
fd; DYTRALMLSTQGFTVALFYCFM           DIHR_MANSE    326    12
fd; DYIMHILMHFQGLLVSTIFCFF           CGRR_HUMAN    366    11
fd; DYVMHILMHYQGLLVSTIFCFF             CGRR_RAT    366    11
fd; RNAQALLLSLQGFTVALFYCFL           DIHR_ACHDO    368    11
fd; MLGSAILQHSQGIFIAVLYCFL               Q93245    295     9
bb;
