\documentclass[border=2px]{standalone}

\usepackage[braket, qm]{qcircuit}
\usepackage{graphicx}

\begin{document}
\scalebox{1.0}{
\Qcircuit @C=1.0em @R=1.0em @!R { \\
	 	\nghost{{qr}_{0} :  } & \lstick{{qr}_{0} :  } & \qw & \qw & \qw\\
	 	\nghost{{qr}_{1} :  } & \lstick{{qr}_{1} :  } & \multigate{5}{\mathrm{instruction}}_<<<{0} & \qw & \qw\\
	 	\nghost{{qr}_{2} :  } & \lstick{{qr}_{2} :  } & \ghost{\mathrm{instruction}}_<<<{1} & \qw & \qw\\
	 	\nghost{{qr}_{3} :  } & \lstick{{qr}_{3} :  } & \ghost{\mathrm{instruction}} & \qw & \qw\\
	 	\nghost{{cr}_{0} :  } & \lstick{{cr}_{0} :  } & \cghost{\mathrm{instruction}} & \cw & \cw\\
	 	\nghost{{cr}_{1} :  } & \lstick{{cr}_{1} :  } & \cghost{\mathrm{instruction}}_<<<{1} & \cw & \cw\\
	 	\nghost{{cr}_{2} :  } & \lstick{{cr}_{2} :  } & \cghost{\mathrm{instruction}}_<<<{0} & \cw & \cw\\
	 	\nghost{{cr}_{3} :  } & \lstick{{cr}_{3} :  } & \cw & \cw & \cw\\
\\ }}
\end{document}